Work

Progress and Prospects of Research on the Role of Phosphatidic Acid in Response to Adverse Stress in Plants

Year: 2025

Type: article

Abstract: Lipid signaling plays a crucial role in how plants perceive and respond to environmental challenges. Among the various lipid mediators, phosphatidic acid (PA) serves as a key metabolic intermediate and second messenger that links membrane dynamics with stress signaling. It is produced rapidly through the coordinated actions of phospholipase C, phospholipase D and diacylglycerol kinase, and its transient accumulation enables plants to adjust defense and acclimation responses with remarkable precision. Recent studies have shown that PA participates in immune signaling, osmotic regulation, and redox control, functioning at the intersection of membrane remodeling and intracellular signal transduction. Through interactions with hormone signaling, calcium fluxes, and reactive oxygen species production, PA integrates multiple stress-responsive pathways, thereby helping to maintain physiological homeostasis under adverse conditions. This review summarizes current understanding of the biosynthetic regulation and signaling roles of PA, and discusses emerging perspectives that highlight its central role in plant immunity and stress adaptation.

Source: Agronomy

DOI: 10.3390/agronomy15122758

Authors: Siqi Xie, Yao Zhao, Menghuan Tao, Yarong Zhang, Zhenfei Guo, Bo Yang

Institution: Nanjing Agricultural University

Language: English

Topic: Plant Stress Responses and Tolerance

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,137

Funders: National Natural Science Foundation of China, Fundamental Research Funds for the Central Universities