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Selective CDK6 Degradation via the KLHDC2 E3 Ubiquitin Ligase

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Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c02713
Authors: Eunhye Jeon, Younghoon Kim, Hyunwoo Ahn, Michael J. Martinez, Kyubin Hwang, Soyeong Cho, Brendan G. Dwyer, Bryan A. Romero, Stephen M. Hinshaw, Nathanael S. Gray, Taebo Sim
Institutions: Yonsei University, Yonsei University Health System, Stanford Medicine, Stanford Cancer Institute, Stanford University
Language: English

Topic: Protein Degradation and Inhibitors
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Ministry of Education, Ministry of Health and Welfare, Korea Health Industry Development Institute, National Research Foundation of Korea, Korea Drug Development Fund, Yonsei University College of Medicine, National Cancer Institute
Awards: G2861942464, G4479424835, G460546115, G8120716183, G8472915027
OpenAlex ID: W4416926908
FWCI: 0.758
Cites: 44
Cited by: 3
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