Year: 2025
Type: article
Study design: Case Report
Abstract: Corticosteroids are effective and relatively inexpensive medications used worldwide for multiple inflammatory diseases. Their use is marred by several well-established side effects, including hyperglycemia, weight gain, osteoporosis, monomorphic corticosteroid-induced acne, gastrointestinal disturbances, cataract, and glaucoma. We report a 29-year-old man with pemphigus vulgaris who achieved disease control with high-dose oral prednisolone and mycophenolate mofetil. While on treatment, he developed blurring of vision from 1 eye and was found to have central serous chorioretinopathy (CSCR). The condition was attributed to high-dose corticosteroid use by the ophthalmologist, who advised discontinuation of the offending drug as soon as possible. A rapid taper of corticosteroids was initiated to preserve vision while maintaining disease control. To our knowledge, CSCR has not been previously described in a patient with pemphigus vulgaris or other cutaneous immunobullous disorders in the English medical literature. This case aims to raise awareness of this rare ocular complication, which, if left untreated, can result in permanent vision loss.
Source: Dermatology Online Journal
DOI: 10.25251/xtg55f12
Authors: Noor us Sabah, Atiya Rahman, Sadaf Bukhari, Beenish Saleem
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $300
OpenAlex ID: W4416927657