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Discovery of Potent, Selective and Efficacious Aminopyrazole Inhibitors of PLK4

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Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c02200
Authors: Joon Won Jeong, Trevor Chang, Jeremy M. Murray, Ryan L. Gonciarz, Justin M. Salvant, Andre H. St. Amant, Sanjay Bhattarai, Jae H. Chang, Jo-Ting Chang, Dana M. Gwinn, Christopher Kochansky, Rhea Matsuura, Leo Mok, Nina M. Muñoz, Andrew G. Raub, David Shaya, Ziqiang Wang, Wei Xu, Kai S. Yang, Heather J. Finlay, Brian A. Sherer
Institution: Exelixis (United States)
Language: English

Topic: Microtubule and mitosis dynamics
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W4416928747
FWCI: 0.837
Cites: 28
Cited by: 2
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