Work

Rational design of a mesoporous COF with tailored porosity for synergistic extraction and analysis of organic ultraviolet stabilizers

Year: 2025

Type: article

Abstract: Organic ultraviolet stabilizers (OUVSs) have raised significant concerns due to their widespread occurrence and potential endocrine-disrupting effects. Herein, a kind of novel mesoporous covalent organic frameworks (COF), i.e., Fe 3 O 4 @TFPB-BD, was rationally designed and fabricated for the vortex-assisted magnetic solid-phase extraction (MSPE) of seven kinds of OUVSs from water samples prior to ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) analysis. The pore size (42.1 Å) of the material was pre-designed using density functional theory (DFT) to match the molecular dimensions of the OUVSs (10.6–12.5 Å), facilitating rapid mass transfer. The adsorption mechanism was elucidated to involve synergistic π-π conjugation and hydrogen bonding interactions. Under optimized MSPE conditions, the developed method demonstrated exceptional performance with a remarkably short pretreatment time of only 8 min, excellent precision (intra-day RSDs of 4.2–14.4%; inter-day RSDs of 1.8–14.8%), and ultra-low detection limits between 0.23 and 0.35 ng/L. The method was successfully applied to the analysis of coastal seawater and swimming pool water, achieving satisfactory spiked recoveries ranging from 83.66% to 118.48%. This study presents a rapid, sensitive, and robust approach for monitoring trace-level OUVSs in complex aquatic environments.

Source: Journal of Chromatography A

DOI: 10.1016/j.chroma.2025.466603