Work

Recurrent Mitral Regurgitation After Transcatheter Edge to Edge Repair

Year: 2025

Type: article

Abstract: BACKGROUND: Recurrent mitral regurgitation (MR) after transcatheter edge-to- edge repair with MitraClip (Abbott) poses clinical and technical challenges. CASE SUMMARY: An 84-year-old man with prior successful MitraClip repair presented with NYHA functional class III dyspnea 1 year later. Imaging showed severe recurrent MR due to progressive leaflet prolapse. Given his comorbidities and high surgical risk, a percutaneous option was chosen. An Amplatzer Valvular Plug III (Abbott) was implanted to treat the dominant jet. Additional MitraClip placement, initially considered, was aborted owing to rising transvalvular gradients. The final result indicated mild MR, hemodynamic improvement, and symptom resolution. DISCUSSION: This case illustrates the feasibility of a tailored, hybrid transcatheter approach in MitraClip failure using a vascular plug, with attention to hemodynamic impact to avoid iatrogenic stenosis. TAKE-HOME MESSAGE: A hybrid strategy, including plug closure, may offer a viable option for recurrent MR after MitraClip in selected patients.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.106324

Authors: Vincenzo Cesario, Nicolas Dumonteil

Institution: Clinique Pasteur

Language: English

Topic: Cardiac Valve Diseases and Treatments

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850