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Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

Year: 2025

Type: article

Abstract: Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years, this tunability has enabled precise control over their interactions with peptides and proteins, opening new avenues in therapeutic and analytical applications. This minireview provides a concise overview of the growing role of ruthenium complexes in protein science, with a focus on latest advances in protein targeting, inhibition, labelling, and sensing.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.202514884

Authors: Liyan Zhang, Yun Chen, Sylvestre Bonnet

Institutions: Leiden University, South China University of Technology, Nanyang Technological University

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Estimated APC paid: $5,510

OpenAlex ID: W4416937219

FWCI: 1.862

Cites: 124

Cited by: 5

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