P16INK4a protein expression associated with Head and Neck Squamous Cell Carcinoma: A perspective of a public health reference service in São Paulo
Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVES: Human Papillomavirus (HPV) may be a predictive biomarker predictor for clinical outcome and influence treatment decisions in patients with Head and Neck Squamous Cell Carcinoma (HNSCC). METHODS: expression was analyzed with epidemiological and clinical variables. RESULTS: . CONCLUSION: , our results are contradictory. It is suggested that future studies in different regions and with a larger sample size should be carried out to confirm these findings, because the patients who participated in the present study are only from a specific region of Brazil. LEVEL OF EVIDENCE: 2B.
Authors: Mariah Cristina Antunes do Nascimento, Ana Lívia Silva Galbiatti-Dias, Lucas Brumato Figueiredo, Ludimila Leite Marzochi, Márcia Maria Urbanin Castanhole-Nunes, Rafael Felipe Maciel Andrade, José Victor Maníglia, Lilian Castiglioni, Juliana Garcia de Oliveira-Cucolo, Érika Cristina Pavarino, Eny Maria Goloni-Bertollo
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,070
OpenAlex ID: W4416949902
