Work

How I do it: sequential robot-assisted stereotactic biopsy and laser interstitial thermal therapy for epilepsy associated with brain tumors

Year: 2025

Type: article

Abstract: BACKGROUND: Laser Interstitial Thermal Therapy (LITT) is a minimally invasive option for treating epilepsy and neuro-oncologic lesions, including those deemed inoperable. However, it does not allow for histomolecular diagnosis. METHODS: We describe our technique for combining stereotactic brain biopsy and LITT, focusing on biopsy sample quantity and its effects on MRI thermometry and ablation quality. CONCLUSION: Stereotactic biopsy can be safely integrated with LITT. Limiting sampling to two specimens minimizes air diffusion and hemorrhagic risk, reducing thermometric artifacts and preserving the accuracy of ablation.

Source: Acta Neurochirurgica

DOI: 10.1007/s00701-025-06705-2

Authors: Oumaima Aboubakr, Bertrand Mathon

Institutions: Centre National de la Recherche Scientifique, Inserm, Sorbonne Université, Pitié-Salpêtrière Hospital, Institut du Cerveau

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,990