Year: 2025
Type: article
Study design: Case Report
Abstract: Primary pulmonary myxoid sarcoma (PPMS) is an extremely rare lung sarcoma with a low incidence. It is a low-grade malignant tumor with histological and molecular features similar to those of extranodal myxoid chondrosarcoma. To date, it has been reported less frequently. We report a case of primary mucinous sarcoma of the lung with EWSR1 translocation, which was definitively diagnosed by bronchoscopic biopsy. Biopsy tissues were tested for pathology, immunohistochemistry, and molecular pathology. Additionally, fluorescence in situ hybridisation was performed using an EWSR1 breakthrough probe. The patient’s left common branch was obstructed by a neoplasm, which was identified during bronchoscopy. A tracheoscopic circling procedure was then performed. The patient underwent a small-incision sleeve resection of the lower lobe of the left lung and lymph node dissection with the assistance of video-assisted thoracic surgery (VATS) under general anesthesia. The patient had a good postoperative recovery, and a follow-up chest CT at 2 months after the operation showed no signs of recurrence.
Source: Frontiers in Medicine
Authors: Chuchu Xu, Xiaona Yin, Xi Wang, Xi Wang, Yongsheng Wang, Xiaoqiong Wang, Xiaoqiong Wang
Institution: Anhui Medical University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4416975872