Work

Tetrahydroquinoline/4,5-dihydroisoxazoline derivatives counteract multidrug resistance in cancer cells by inhibiting P-glycoprotein (ABCB1)-mediated transport

Year: 2025

Type: article

Source: Biochimica et Biophysica Acta (BBA) - General Subjects

DOI: 10.1016/j.bbagen.2025.130894

Authors: Marina Hembecker, Diogo Henrique Kita, Azam Rashidian, Luis C. Vesga, Bruna Estelita Ruginsk, Arnold R. Romero Bohórquez, Stelia Carolina Mendez-Sanchez, Vinicius Goncalves Maltarollo, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Antti Poso, Katalin Goda, Suresh V. Ambudkar, Vivian Rotuno Moure, Thales Kronenberger, Glaucio Valdameri

Institutions: Universidade Federal do Paraná, National Institutes of Health, National Cancer Institute, Center for Cancer Research, German Center for Infection Research, Universidad Industrial de Santander, Universidade Federal de Minas Gerais, University of Eastern Finland, University of Debrecen, University of Tübingen

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Deutsches Zentrum für Infektionsforschung, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Fundação Araucária, National Institutes of Health, National Cancer Institute

Awards: G2252644519, G4343107319, G4363155131, G6873576236

OpenAlex ID: W4416978263

FWCI: 0.362

Cites: 41

Cited by: 1

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