Work

Modeling spectroradiometric measurements of oral mucosal tissue autofluorescence

Year: 2025

Type: article

Abstract: Spectroradiometric fluorescence measurements were collected from the dorsal tongue and inner lip of healthy volunteers. These sites were chosen to represent the distinct spectral features that differentiate keratinized from non-keratinized oral tissues, as documented in previous studies. A computational model was then applied to estimate the relative contributions of key fluorophores and to quantify the influence of blood absorption on the observed fluorescence spectra. The resulting dataset and model, both freely available, serve as reference standards for healthy oral tissue and support the development of quantitative, non-invasive imaging systems for consistent and reproducible assessment of oral mucosal health.

Source: Biomedical Optics Express

DOI: 10.1364/boe.575722

Authors: Joyce E. Farrell, Xi Mou, Brian A. Wandell

Institution: Stanford University

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,913