The association between social drivers of health, HIV status and physical activity with perceived stress in U.S. women with or without HIV
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: The physiological adaptation to chronic stress can have deleterious health effects. Although higher physical activity (PA) has been linked to lower stress, it is unknown whether social driver of health (SDOH) burden and HIV status impact the stress reduction effects of PA due to their unique contributions to stress. METHODS: Using a cross-sectional sample (n = 444) from the Women's Interagency HIV Study during 2014-2019, multivariate linear regression modeling was used to estimate the effect of SDOH burden and PA on stress. SDOH burden was defined as the sum of individual-level indicators: inadequate housing, income, and education as well as unemployment, and food insecurity. RESULTS: = 0.22 [p < .001], -0.10 [p < .05], and - 0.11 [p < .05] respectively) After adjusting for age, HIV status and race, and including both SDOH and PA, only SDOH predicted stress (β = 0.20, 95% CI [0.6, 1.87]; p < .001). Among this sample, food insecurity was the strongest predictor of stress, reducing the effects of PA when included in the model (β = 0.24, 95% CI [2.38, 5.99]; p < .001). CONCLUSIONS: Findings indicated that, after adjusting for age, HIV status and race, SDOH burden reduced the association between PA and stress, and was a stronger predictor of stress in women living with HIV than those living without HIV. The impact of food insecurity appears to be a powerful driver of stress in both women living with and without HIV.
Source: BMC Public Health
Institutions: University of Mississippi Medical Center, University of Alabama at Birmingham, University of North Carolina at Chapel Hill, Albert Einstein College of Medicine, University of California, San Francisco, UAB Medicine, University of Miami, SUNY Downstate Health Sciences University, Johns Hopkins University, John H. Stroger, Jr. Hospital of Cook County, Cook County Health and Hospitals System, Georgetown University, Columbia University
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,290
Funders: Indiana Clinical and Translational Sciences Institute, Northwestern University, Mucolipidosis IV Foundation, Georgia Clinical and Translational Science Alliance, National Institutes of Health, University of California, San Francisco, Center for AIDS Research, University of Alabama at Birmingham, National Institute on Alcohol Abuse and Alcoholism, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute on Drug Abuse, National Cancer Institute, National Institute on Deafness and Other Communication Disorders, National Institute of Nursing Research, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Institute of Dental and Craniofacial Research, National Center for Advancing Translational Sciences, National Institute on Minority Health and Health Disparities, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Center for AIDS Research, University of North Carolina at Chapel Hill, Clinical and Translational Science Institute, University of California, Los Angeles
Awards: G1034546755, G1296759572, Translational Biomedical Science Training Grant, G1913134163, G1972383081, Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS), G2008237588, G311558797, G3869857964, G4044828089, G5147848267, G5660189159, G5863844756, Clinical and Translational Science Institute, G5900455136, G6396423216, University of Miami Developmental HIV/AIDS Mental Health Research Center (D-ARC), G6745172908, G6990385686, G7152846654, Institutional Career Development Core, G775892330, G7760075911, G7807729167, Johns Hopkins Institute for Clinical and Translational Research, G9000080293, G9000082816, University of Pittsburgh MACS/WIHS CCS, MACS/WIHS -CCS, ERC Einstein-Rockefeller-CUNY Center for AIDS research, SF Bay Area MACS/WIHS Combined Cohort Study, UNC MACS/WIHS Combined Cohort Study Clinical Research Site, Surviving the HIV Epidemic (S/HE) in metropolitan Washington DC - Advancing knowledge through cohort studies, Center for AIDS Research at Emory University, Northwestern CORE Clinical Research Site: Trans-omics for HIV/AIDS Research, Los Angeles CRS for the MACS/WIHS Combined Cohort Study, Data Analysis and Coordination Center for the MACS-WIHS Combined Cohort Study, MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS), The University of North Carolina Center for AIDS Research, MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS), Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC Center, Atlanta MACS/WIHS Combined Cohort Study Clinical Research Site, UAB-MISS MACS/WIHS Combined Cohort Study, Miami Center for AIDS Research, UCLA Clinical and Translational Science Institute, Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS), UAB Center for AIDS Research (CFAR)
OpenAlex ID: W4416668690