Work

Chinese expert consensus on the treatment and diagnosis of moyamoya disease and moyamoya syndrome (2024)

Year: 2025

Type: article

Abstract: AIM: Moyamoya disease (MMD) is a chronic, occlusive cerebrovascular disorder with no unified management guidelines. This consensus aims to provide updated, evidence-based recommendations for the diagnosis and treatment of MMD. METHODS: We integrated recent findings from epidemiology, genetics and imaging studies-particularly those published since 2017-along with expert input from over 20 clinical centres. Advances in diagnostic criteria, treatment strategies and perioperative management were reviewed and incorporated to update the 2017 consensus. RESULTS: Refinements in diagnosis include high-resolution imaging and revised Suzuki staging supplemented by new collateral circulation grading. Treatment strategies emphasise individualised surgical planning, especially extracranial-intracranial bypass, and pharmacological management targeting ischaemic events, cognitive decline and collateral vessel formation. Perioperative care focuses on managing complications such as transient neurological dysfunction and stroke through haemodynamic monitoring and timely imaging. CONCLUSIONS: This updated consensus underscores the value of early diagnosis using advanced imaging, personalised interventions and standardised perioperative care. This initiative aims to enhance clinical outcomes and health-related quality of life in MMD patients, offering a contemporary, evidence-based approach to managing MMD.

Source: Stroke and Vascular Neurology

DOI: 10.1136/svn-2024-003925

Authors: Wei Ni, Jiabin Su, Yuchao Fei, Yuxiang Gu, Ying Mao, Shuo Wang