Work

Synthesis of an Amphiphilic Polymer With Adjustable Surface Charge and Polarity and its Use for Obtaining Water‐Soluble Nanoparticles

Year: 2025

Type: article

Abstract: Amphiphilic copolymers can be effectively used to encapsulate a broad range of nanomaterials. Since the surface charge and charge distribution can strongly affect relevant effects like protein adsorption, effective routes are required to tune it. Herein, a straightforward strategy is presented to tune the formal charge of poly (isobutylene‐ alt ‐maleic anhydride), converting it into an amphiphilic polymer with negative charge, zwitterionic character, or positive charge. This is a route of surface modification in which impact on other colloidal parameters apart for surface charge is minimized. The encapsulation of quantum dots are tested with the resulting polymers and confirm their robust stabilization over a range of pH values and ionic strengths.

Source: Advanced Synthesis & Catalysis

DOI: 10.1002/adsc.70136

Authors: Chenxi Yang, Saad Megahed, Miao Feng, Alaaldin M. Alkilany, Florian Schulz, Wolfgang J. Parak

Institutions: Universität Hamburg, Al-Azhar University, Qatar University

Language: English

Topic: Advanced Polymer Synthesis and Characterization

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,650