Burn injuries in the Asia-Pacific region: Use of polyhexamethylene biguanide and betaine surfactant (PHMB-B) for wound bed preparation in children and adults
Year: 2025
Type: article
Abstract: This case-series supplement serves as an educational resource for health professionals involved in the care of burn injuries. Drawing from clinical experiences across healthcare settings in the Asia-Pacific region, the supplement focuses on the use of polyhexamethylene biguanide and betaine surfactant (PHMB-B) solution, gel and high-viscosity gel, alone or in combination, in managing both thermal and non-thermal burns, including partial-thickness and full-thickness burns, in both paediatric and adult populations. In alignment with international guidance, this supplement reinforces the recommendation to integrate PHMB-B into routine practice. The broad-spectrum antimicrobial activity, low cytotoxicity and biofilm-disruptive properties of this combined solution is clinically appropriate for use in complex burn wounds, where infection control and optimal healing conditions are crucial to wound healing.
Source: Journal of Wound Care
Authors: Harikrishna KR Nair, Pornprom Muangman, Yan Liu, Kerrie Coleman, Wipawee Kanpuan, Mohd Shahrul Suondoh, Salmi Mohamed Sukur, Anchan Ketmek, Suttipong Tianwattanatada, Suchada Kittidacha, Orapin Taengthet, Wen Liang Wang, Min Gao, Zong Qi Yin, Yi Dou, Jia Jun Zhu, Chenlu Song, Gai Zhang, Xuechuan Li, Huizhong Yang, Duong Van Phu, Nguyen Hai An, Claudine Rosario B Lukban, Gerald Marion M Abesamis, Ralf V Santamaria, Fernando A Acance, Deni Alia Yadi, Amelia Ganefianty, Abdurrahman Hakim, Chamath Sachindra Angulugaha, Gayan Ekanayake, SVP Wimalarathna, Mohd Shahrul Suondoh, Salmi Mohamed Sukur, Thanchanock Sawangsangwattana, Tippawan Wattanakham, Amarmend Ganbat
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4416999955