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Precision targeting of pathogenic B cells and autoantibodies in systemic lupus erythematosus using CAR T cells against the IGHV4-34 B cell receptor

Year: 2025
Type: conference-abstract
Source: Blood
DOI: 10.1182/blood-2025-4120
Authors: Audrey Bochi-Layec, Ivan Cohen, Jean Lemoine, Scott Jenks, Pedram Bayat, Ki Hyun Kim, Huiwu Zhao, Ositadimma Ugwuanyi, Federico Stella, Guido Ghilardi, Giulia Gabrielli, Sarah McCuaig, Anastasia Iatrou, Elisavet Vlachonikola, Maria Karypidou, Eleni Bouziani, Ranjani Ramasubramanian, Andreas Agathangelidis, Luca Paruzzo, Regina Bugrovsky, Puneeth Guruprasad, Li-Ping Wang, Jaryse Harris, Yunlin Zhang, Raymone Pajarillo, Portia Kreiger, Bria Fulmer, Marcos Cases, Patrizia Porazzi, E. John Wherry, Sokratis Apostolidis, Vijay Bhoj, Stephen J. Schuster, Paolo Ghia, Kostas Stamatopoulos, Edward Behrens, Ignacio Sanz, Marco Ruella
Institutions: Hospital of the University of Pennsylvania, Abramson Cancer Center, University of Pennsylvania, Emory University, Children's Hospital of Philadelphia, Centre for Research and Technology Hellas, Vita-Salute San Raffaele University, IRCCS Ospedale San Raffaele
Language: English
Subfield: Rheumatology
Field: Medicine
Open Access status: closed
OpenAlex ID: W4417022002
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