Clinical spectrum of osteomalacia: an atypical presentation
Year: 2025
Type: article
Study design: Case Report
Abstract: Osteomalacia is a metabolic bone disorder characterized by defective mineralization of the osteoid matrix, primarily due to vitamin D deficiency, calcium, or phosphate imbalance. This case highlights the classical clinical and radiological presentation of osteomalacia. A 45-year-old female presented with a history of persistent pain in the right leg for the past two years. She had a known history of hypertension and was on Telma 20 mg once daily. She also reported a previous fall from a bike, which resulted in a tibial fracture. She was admitted to the orthopedics department at that time and underwent surgery. Laboratory investigations revealed low vitamin D levels (8 ng/mL) and reduced calcium levels (1.80 mmol/L), and the patient was diagnosed with osteomalacia. She now presented for the management of persistent pain and generalized bone weakness. A radiographic evaluation (X-ray) demonstrated an implant in the right tibia, and the bones appeared markedly osteopenic and fragile. Laboratory investigations revealed vitamin D levels (25 ng/mL) and calcium levels (2.34 mmol/L). The patient was managed with local massage using Balashwagandha Taila, Tab. Amyron (1 tablet twice daily), Cap. Uprise D3 60,000 IU (once weekly), and Tab. Shallaki (1 tablet twice daily) for two months, which resulted in a significant reduction of pain. This case underscores the importance of correlating clinical findings with radiological features for the timely recognition and management of osteomalacia.
Source: Pan African Medical Journal
Authors: Mahesh Sharma, Sourabh Deshmukh
Language: English
Topic: Vitamin D Research Studies
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $180
OpenAlex ID: W4417027895
FWCI:
Cites:
Cited by:
Related to: