New insights into clinical strategies for acute coronary syndrome based on biomarker-driven multiomics research
Year: 2025
Type: article
Abstract: With rapid advancements in genomics, proteomics, and metabolomics researchers have gained significant insights into ACS (ACS) pathogenesis. Studies have revealed specific biomarkers linked to ACS and provided novel tools for risk evaluation and early diagnosis. Genomic breakthroughs have enabled exploration of genetic factors contributing to ACS. Transcriptomics has facilitated the analysis of gene expression alterations in patients with ACS. Proteomics has identified potential therapeutic targets by pinpointing biomarkers, paving the way for new drug development. Advances in metabolomics have enabled monitoring of changes in metabolic pathways, offering valuable information for early diagnosis and disease prognosis. In summary, multiomics research has shed light on the critical aspects of ACS clinical strategies, facilitating advancements in early diagnosis, risk assessment, and personalized therapy, and will increasingly assume a pivotal role in future clinical practice.
Authors: Zhixuan Zhao, Keying Yu, Yuetong Zhao, Tenghui Tian, Rui Shi, Jinyue Zhao, Hang Yu, Di Gao, Da Song, Liping Chang, Yue Deng
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Awards: G2657483792, G8463723427
OpenAlex ID: W4417031628