Work

COCOMAPS 2.0: a web server for identifying, analyzing, and visualizing atomic interactions at the interface of biomolecular complexes

Year: 2025

Type: article

Abstract: SUMMARY: Herein, we present COCOMAPS 2.0, for the analysis, visualization, and comparison of the interface in protein-protein and protein-nucleic acid complexes. COCOMAPS 2.0 complements the residue-level and buried surface area analyses of the original COCOMAPS tool with a comprehensive and accurate atomic-level characterization of the interface, enabling detailed interpretation of molecular recognition. Furthermore, it provides a greatly enhanced flexibility, interactivity, and efficiency in graphical visualizations. AVAILABILITY AND IMPLEMENTATION: COCOMAPS 2.0 is accessible as a public web tool at https://aocdweb.com/BioTools/cocomaps2 and as a standalone code at https://doi.org/10.5281/zenodo.17390665.

Source: Bioinformatics

DOI: 10.1093/bioinformatics/btaf606