Chronic Diarrhoea in Hyperthyroidism Leading to Rectal Prolapse: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Rectal prolapse is typically associated with chronic constipation and pelvic floor dysfunction. However, its occurrence secondary to chronic diarrhoea from hyperthyroidism is exceptionally rare. This case emphasises a rarely discussed pathophysiological link between prolonged thyrotoxicosis and advanced rectal prolapse. In this report, a 67-year-old male presented with chronic diarrhoea and rectal prolapse for two years, along with classic hyperthyroid features like weight loss and a longstanding multinodular goitre. Clinical and hormonal evaluation confirmed uncontrolled hyperthyroidism, while local examination revealed Grade V rectal prolapse. Imaging and endoscopic workup ruled out malignancy or other structural causes. He was managed conservatively with antithyroid drugs, dietary changes, and pelvic floor rehabilitation. Uncontrolled hyperthyroidism can present atypically with advanced rectal prolapse due to persistent diarrheal episodes and weakened pelvic support. Early recognition, endocrine optimisation, and multidisciplinary care are pivotal in such rare yet clinically significant presentations.
Authors: Samina Ruquaya, K Vivekananda Subramania Nathan, M Reegan Jose, Najeem Fazil
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $275
OpenAlex ID: W4417034129
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