Evaluation of Contrast Enhancement Uniformity and Contrast Media Optimization in Chest-to-lower Extremity CTA Using Variable Helical Pitch Scanning
Year: 2025
Type: article
Abstract: PURPOSE: This study aimed to evaluate the usefulness of variable helical pitch scanning (vHP) on the uniformity of contrast enhancement in wide-range computed tomography angiography (CTA) from the chest to the lower extremities using contrast media administered at 400 mgI/kg over 20 seconds. METHODS: Using the double-level test bolus injection (DLTI) method to determine the contrast arrival time, CTA scans were performed with a fixed-HP method (n=20) and a variable-HP method using vHP (n=20). The CT numbers at five major arterial regions were compared, and a visual assessment was also conducted. RESULTS: Compared with the fixed-HP method, the variable-HP method significantly increased the CT number in the abdominal aorta and femoral arteries (p<0.05) and improved the uniformity of contrast enhancement along the body axis. The visual assessment also showed significantly higher ratings for the variable-HP method (p<0.05). CONCLUSION: The protocol combining DLTI and vHP techniques is useful for achieving more uniform contrast enhancement from the chest to lower extremities in CTA while reducing the contrast medium volume, and is expected to improve diagnostic performance.
DOI: 10.6009/jjrt.26-1599
Author: Yuichi Takao
Institution: Fukuoka Tokushukai Hospital
Language: English
Topic: Radiation Dose and Imaging
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4417035658