Work

Novel oil-in-ionic liquid microemulsion extraction and in situ liquid–liquid microextraction of natural phenolic compounds from functional foods

Year: 2025

Type: article

Abstract: A novel ultrasonic-assisted oil-in-ionic liquid microemulsion extraction and in situ liquid–liquid microextraction method was developed via integrating ultrahigh-performance liquid chromatography and quadrupole time-of-flight mass spectrometry to determine phenolic compounds in functional foods. During experimentation, a series of factors affecting the extraction efficiency were optimized, such as types and contents of microemulsion components, salt amount, pH value of microemulsion, and ultrasonic time. Furthermore, a response surface methodology was applied to optimize the extraction conditions. Under the optimized conditions, the method presented a linear relationship in the range of 0.08–4 μg/mL, with correlation coefficients ranging from 0.9967 to 1.0000. Intraday (n = 6) and interday (n = 6) precision levels of the method were <4.91 %, which was within the acceptable range. The limits of detection and quantification were 2.06–30.77 and 6.86–102.56 ng/mL, respectively. The method was successfully applied to Tetrastigma hemsleyanum to attain a recovery ranging 89.44 %–109.34 %.

Source: LWT

DOI: 10.1016/j.lwt.2025.118864

Authors: Xin Peng, Huang-Fei Jin, Jun Cao, Li-Hong Ye

Institutions: Zhejiang Chinese Medical University, Hangzhou Normal University, Hangzhou Red Cross Hospital

Language: English

Topic: Analytical chemistry methods development

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $3,240

Funder: Natural Science Foundation of Zhejiang Province