ROS-Responsive Double-Layer Microneedles Enable Sequential Antibacterial and Immunomodulatory Therapy for Infected Wound Healing
Year: 2025
Type: article
Abstract: This study proposes an innovative therapeutic strategy that combines dual-drug delivery, oxidative microenvironment regulation, and immune modulation to promote the healing of chronic infected wounds. The MN@DOX+RES microneedles system demonstrates great potential in overcoming clinical challenges associated with infection, inflammation, and the limitations of conventional therapeutic approaches.
Source: Theranostics
DOI: 10.7150/thno.122865
Authors: Huifang Zhang, Zhongke Wang, Yujing Zhu, Ting Huang, Ziliang Xiu, Haozhe Huang, Hankai Li, Jing Xie, Haixia Huang, Min Liu, Libo Sun, Yuyan Lan, Ling Guo
Language: English
Topic: Wound Healing and Treatments
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,671
OpenAlex ID: W4417068294