Work

LPC-engineered liposomes activate transcytosis for paclitaxel brain delivery and potentiation of TTFields/TMZ via TALECT regimen in glioblastoma

Year: 2025

Type: article

Abstract: This work presents a novel transcytosis-activating platform for BBB penetration and proposes the clinically translatable TALECT regimen, advancing the cost-effectiveness of TTFields-based GBM therapy.

Source: Theranostics

DOI: 10.7150/thno.122658

Authors: Qi Zhan, Kaikai Yi, Shixue Yang, Biao Hong, Dongyuan Su, Jixing Zhao, Qixue Wang, Xiaoteng Cui, Yanping Huang, Yaqing Ding, Chunchao Cheng, Jiasheng Ju, Chunsheng Kang

Institutions: Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin Medical University Cancer Institute and Hospital

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,671

OpenAlex ID: W4417068295

FWCI: 0.751

Cites:

Cited by: 4

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