Work

Discovery and Optimization of Novel Tricyclic Ubiquitin-Specific Protease 1 Inhibitors for the Treatment of BRCA-Mutated Breast Cancer

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c01221

Authors: Tianning Xiong, Hong Yang, Songwen Lin, Li Sheng, Junpu Ge, Jinhua Wang, Heng Xu

Institution: Chinese Academy of Medical Sciences & Peking Union Medical College

Language: English

Topic: Ubiquitin and proteasome pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Chinese Academy of Medical Sciences

Awards: G2174198254, G2381989466, G5949953664

OpenAlex ID: W4417068585

FWCI: 0.783

Cites: 31

Cited by: 3

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