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Unilateral Extremity Swelling, a Rare Manifestation of Scleredema Adultorum of Buschke in a Child: Case Report

Year: 2025

Type: article

Abstract: Scleredema adultorum of Bushcke is a rare connective tissue disorder that is characterized by skin thickening that commonly starts from the neck and spreads to the face, shoulders, upper back, abdomen, and in some cases, thighs. The symptoms are generally seen after an infection associated with streptococcus. Atypical clinical manifestations of the disease have been reported in a 13-year-old boy, who developed unilateral lower extremity swelling of the right thigh and leg and was admitted to the hospital with the primary diagnosis of Deep vein thrombosis (DVT). The ultimate diagnosis of scleredema adultorum of Buschke with an uncommon manifestation was established based on the clinical symptoms and ASO titers. This case has been reported to emphasize the importance of the unique signs and symptoms of the disease, leading to uncommon differential diagnosis which requires extensive investigation.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.71639

Authors: Shabnam Hajiani Ghotbabadi, Dorna Derakhshan, Rida Rubab Amir, Pooneh Tabibi

Institutions: Shiraz University of Medical Sciences, Alborz University of Medical Sciences

Language: English

Topic: Systemic Sclerosis and Related Diseases

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820