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Association Between Mental Health and Metabolic Dysfunction–Associated Fatty Liver Disease

Year: 2025

Type: article

Abstract: Depression has recently been identified as a potential predisposing factor for metabolic dysfunction-associated fatty liver disease (MAFLD) among adults in the US. This cross-sectional, nationwide study examined the association between mental health and MAFLD in Korean adults. Mental state was addressed using a question for suicidal ideation and depressive mood, and MAFLD was assessed according to the criteria established by an international expert panel. A stepwise multivariate logistic regression analysis revealed that MAFLD was significantly more common in men with suicidal ideation and in women with depressive mood compared with their non- suicidal and non-depressed counterparts, respectively. These results warrant mental health screening among patients with MAFLD. Key Words: Depression, Metabolic diseases, Fatty liver disease, Suicidal ideation.

Source: Journal of College of Physicians And Surgeons Pakistan

DOI: 10.29271/jcpsp.2025.12.1633

Authors: Ji Hyeon Park, Yoo Jeong Lee, In Cheol Hwang, Hong Yup Ahn

Institutions: Dongguk University, The Catholic University of Korea Seoul St. Mary's Hospital, Catholic University of Korea, Korea University Guro Hospital, Gachon University, Gachon University Gil Medical Center

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4417070728

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