Work

Nanoantioxidants and Their Potential Use in the Management of Oxidative Stress-Associated Male Infertility

Year: 2025

Type: article

Abstract: The prevalence of male infertility attributed to oxidative stress (OS) is a growing concern globally. Traditional methods to treat male infertility have some limitations, including low efficacy and invasiveness. Additionally, assisted reproductive procedures, such as in vitro fertilization and intracytoplasmic sperm injection, are expensive and carry higher risks. These challenges underscore the need for innovative solutions. A multidisciplinary approach is imperative, drawing insights from fields such as reproductive biology, nanotechnology, and clinical research to effectively combat male infertility caused by OS. Recent advancements in nanobiotechnology provide a promising opportunity to tackle male infertility caused by OS. These advancements enable the design and development of nanoantioxidants (nanoAOXs) and drug delivery systems tailored to the male reproductive environment. This review highlights the recent progress in the rational design of nanomaterials, with a specific focus on nanoAOXs for managing male infertility associated with OS.

Source: Frontiers in Bioscience-Landmark

DOI: 10.31083/fbl39945

Authors: Zahra Bakhtiary, Yasaman Eyvazi, Renata Finelli, Saradha Baskaran, Suresh C. Sikka, Manesh Kumar Panner Selvam

Institutions: Tulane University, London Women's Clinic

Language: English

Topic: Sperm and Testicular Function

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500