Year: 2025
Type: article
Abstract: The digestive tropism of SARS-CoV-2 due to the presence of the same ACE2 receptor in the digestive system as in the respiratory system raised the question of the role of fecal-oral transmission in the pandemic. The aim of this study was to explore oral infection in hamsters model. SARS-CoV-2 inoculation via the oral and intranasal routes resulted in comparable infection in hamsters. In addition to implications for human health, oral infection could have implications for potential animal reservoirs.
Source: PLoS ONE
Institutions: Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail, Inserm, Université Paris Cité, AgroParisTech, Université Paris-Saclay, Microbiologie de l’alimentation au service de la santé, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Physiopathologie et pharmacotoxicologie placentaire humaine : Microbiote pré & post natal, Oniris, Physiopathologie Animale et bioThérapie du muscle et du système nerveux, Université de Lyon, VetAgro Sup, PiLeJe (France)
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,382
OpenAlex ID: W4417076695