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Unmasking BRASH Syndrome: A Clinical Challenge in Bradycardia and Renal Dysfunction

Year: 2025
Type: article
Abstract: The term BRASH refers to a clinical constellation characterized by bradycardia, renal dysfunction, atrioventricular (AV) nodal-blocking medication exposure, shock, and hyperkalemia. Although the condition represents a fully reversible cause of symptomatic bradycardia, it frequently goes unrecognized. Prompt identification and a clear understanding of its underlying mechanisms are essential to avoid unnecessary procedures. The syndrome should be suspected when a patient presents with bradycardia in the setting of impaired kidney function and elevated serum potassium, particularly when there is recent or ongoing use of AV nodal-blocking agents. Early recognition is critical because effective management requires addressing each contributing factor simultaneously, rather than treating a single abnormality in isolation.
Source: Cureus
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4417146664
FWCI:
Cites: 5
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