Work

Spatial and temporal dispersion of ventricular repolarization in pediatric patients with congenital long QT syndrome

Year: 2025

Type: article

Abstract: Congenital long QT-syndrome (LQTS) is a genetic disorder characterized by prolonged corrected QT-intervals (QTc, Bazett’s formula) longer than 450ms in males and 460 ms in females on the 12-lead surface electrocardiogram (ECG). This syndrome is caused by mutations in genes encoding ion channels, prolonging cardiac repolarization.1 Consequently, LQTS may give rise to life-threatening ventricular tachyarrhythmias and is a leading cause of sudden cardiac death (SCD) in young individuals without structural heart abnormalities.

Source: HeartRhythm Case Reports

DOI: 10.1016/j.hrcr.2025.11.027