The relationship between motoric cognitive risk syndrome and all-cause mortality in older people: findings from CHARLS 2011–2023
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: This study aims to investigate the association between motoric cognitive risk (MCR) syndrome, defined by the coexistence of slow gait and subjective cognitive complaints, and all-cause mortality among older adults in China, providing evidence to support early identification and intervention strategies for MCR in aging populations. METHODS: Data were drawn from the China Health and Retirement Longitudinal Study (CHARLS, 2011–2023), including 6,304 participants aged 60 years and older. A Cox proportional hazards model was used to examine the association between MCR and all-cause mortality, adjusting for demographic characteristics, lifestyle behaviors, health status, chronic diseases, and metabolic biomarkers. RESULTS: The study found an association between MCR and all-cause mortality in older adults. Among the participants, 15.5% (934/6,304) died during the follow-up period, with 20.9% (256/1,227) from the MCR group and 13.4% (678/5,077) from the non-MCR group. The median follow-up time was 144 months in the MCR group and 120 months in the non-MCR group. The Cox proportional hazards model indicated that MCR was associated with a higher risk of all-cause mortality (HR = 1.54, 95% CI: 1.34–1.78), and this association remained significant after adjusting for all confounders (HR = 1.46, 95% CI: 1.27–1.70). CONCLUSION: This study confirms that MCR is associated with an increased risk of all-cause mortality in older people.
Source: Archives of Public Health
Authors: Xiang Li, Chao Wei, Kejing Hu, Jie Sun, Xiang Gao, Jianhong Yang
Language: English
Topic: Frailty in Older Adults
Subfield: Geriatrics and Gerontology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,990
Award: G7909746008
OpenAlex ID: W4417148154