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Psilocybin in Alcohol Use Disorder Maintains Abstinence Efficacy: A Scoping Review

Year: 2025

Type: preprint

Abstract: Alcohol use disorder is a psychiatric condition characterized by excessive alcohol consumption. The drugs that are used to treat it often fail to prevent relapse. At the same time, psilocybin is increasingly being investigated for the treatment of various substance use disorders. This review aims to evaluate the results of the most recent clinical trials assessing psilocybin as a treatment for alcohol use disorder. According to these trials, psilocybin seems to reduce craving but its effect on overall alcohol consumption is less clear. There is no doubt that future trials would benefit from larger sample sizes and standardized tests.

Source: Qeios

DOI: 10.32388/xcfsag.2

Authors: Jacques Suspène, Sarah Huet, Sabine Berteina-Raboin, Amine Benyamina, Patrick Baril, Séverine Morisset-Lopez, Raphaël Serreau

Institutions: École Normale Supérieure - PSL, Centre National de la Recherche Scientifique, Université d'Orléans, Hôpital Paul-Brousse, Centre de Biophysique Moléculaire

Topic: Psychedelics and Drug Studies

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4417165392

Cites: 43

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