Work

Retrospective Comparison of Conventional Triple Therapy and Levofloxacin-Based Sequential Therapy for Helicobacter pylori Eradication in Mardan Medical Complex

Year: 2025

Type: article

Abstract: OBJECTIVE: This study aims to compare, using record-based data, the clearance proportions of the conventional triple management regimen and the levofloxacin-based sequential management regimen in patients treated at Mardan Medical Complex. METHODS: infection. Data were collected for demographics, management regimens, and post-management stool antigen results. Statistical analyses included Chi-square and independent t-tests (p < 0.05 notable). RESULTS: Among 238 patients, clearance was obtained in 62% of those receiving the triple management regimen and 80% of those receiving the sequential management regimen (χ² = 9.03, p = 0.003). The sequential management regimen showed greater clearance and better tolerance. CONCLUSION: Sequential management regimen obtained superior clearance proportions and should be preferred in areas with high clarithromycin resistance.

Source: Cureus

DOI: 10.7759/cureus.98803

Authors: M Naeem, Manzoor Hussain

Institution: Mardan Medical Complex, Mardan

Language: English

Topic: Helicobacter pylori-related gastroenterology studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4417165745