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Transcatheter Closure for Prevention of Stroke in an Octogenarian Woman With Dual Left Atrial “Appendages”

Year: 2025

Type: article

Abstract: Thrombosis-induced stroke represents one of the most serious complications of atrial fibrillation (AF), and the presence of spontaneous echo contrast (SEC) is a well-established echocardiographic predictor of pre-thrombotic states. An 82-year-old woman with AF presented with recurrent ischemic strokes despite oral anticoagulation therapy and was referred to our center for left atrial appendage closure (LAAO). Transesophageal echocardiography (TEE) demonstrated slow flow within the left atrial appendage along with a large atrial septal aneurysm (ASA) exhibiting prominent SEC. Following multidisciplinary evaluation, simultaneous percutaneous closure of both the LAA and the ASA/PFO was successfully performed. Postprocedural follow-up demonstrated no device-related thrombosis, peri-device leak, or further stroke events. This case underscores the potential benefit of combined LAA and ASA/PFO closure in high-risk AF patients with recurrent embolic events despite anticoagulation.

Source: Catheterization and Cardiovascular Interventions

DOI: 10.1002/ccd.70415

Authors: Tao He, Cong Lu, Zhenni Zhang, Jie Zeng

Institutions: University of Electronic Science and Technology of China, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu University of Traditional Chinese Medicine, Southwest Medical University

Language: English

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4417181063

FWCI:

Cites: 13

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