Work

Choroidal Metastasis of a Cutaneous Melanoma: A Case Report

Year: 2025

Type: article

Abstract: Introduction: We report the clinical, imaging, histopathological, and genetic features of a choroidal metastasis originating from a cutaneous melanoma. Case Presentation: A 92-year-old woman presented with an asymptomatic pigmented lesion in her right eye. She had a history of prior cutaneous melanoma. Workup revealed widespread metastases to the liver, lungs, and brain. Histopathology (post-mortem eye) showed melanoma cells of the epithelioid cell type. Genetic analysis was positive for the BRAF V600K variant, confirming the cutaneous origin of the choroidal tumour. Conclusion: Choroidal metastasis of a cutaneous melanoma is a rare manifestation that can be mistaken for a primary choroidal melanoma. A comprehensive clinical history, histopathology, and genetic analysis are useful in distinguishing between the two entities.

Source: Case Reports in Oncology

DOI: 10.1159/000549491

Authors: Jacky Jiang, Ebrar Al-Yasery, Jackson Chee Chea Lee, Penny McKelvie, Alan Luckie

Institutions: UNSW Sydney, Albury Wodonga Health, St Vincent's Hospital Melbourne

Language: English

Topic: Ocular Oncology and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,170