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Supplementary Figure 5 from A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability

Year: 2025

Type: supplementary-materials

Abstract: Supplementary Figure S5: CDKN1A EMSA gels and intensity plots (A) EMSA for p53 WT-CL. (B) EMSA for p53 Y220C-CL. (C) EMSA for p53 Y220C-CL complexed with KG13. (D) EMSA for p53 R273C-CL. (E) Upper band intensities plotted for each protein construct. (F) Upper band intensities plotted for p53 R273C-CL.

DOI: 10.1158/2159-8290.30849197

Authors: Keelan Z. Guiley, Kevan M. Shokat

Language: English

Topic: Cancer-related Molecular Pathways

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

OpenAlex ID: W4417194816

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