Work

Valve Creation From Atrial Appendage Tissue for Primary Repair of Tetralogy of Fallot in Infants

Year: 2025

Type: article

Abstract: We assessed the reintervention rate, pulmonary valve function, and neopulmonary valve (NPV) annulus growth after primary tetralogy of Fallot (ToF) repair with NPV creation from right atrial appendage tissue, retrospectively comparing data from 19 ToF patients who underwent primary repair with NPV creation with a historical cohort of patients who underwent transannular patch (TAP) repair. The median age at NPV surgery was 3.5 months. No mortality was observed. The reintervention rate was similar between the NPV and TAP groups (5% vs 11%, respectively; P = 0.066). At 12 months, 56% of the NPV patients had freedom from moderate or greater pulmonary regurgitation, and the NPV annulus exhibited growth. NPV creation from right atrial appendage tissue is safe and can prevent early pulmonary regurgitation after ToF repair.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.105908

Authors: Seth M. Harris, Jacob R. Miller, Manish Aggarwal, Matthew Canter, Fei Wan, Pirooz Eghtesady

Institution: Washington University in St. Louis

Language: English

Topic: Congenital Heart Disease Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850