Work

Narrowed pulse pressure as a predictor of active hemorrhage in hemodynamically stable blunt trauma: Insights from an Asian cohort

Year: 2025

Type: article

Abstract: Objective: This study aimed to assess the predictive value of pulse pressure (PP) for identifying the critical administration threshold (CAT) in hemodynamically stable patients with active bleeding following blunt trauma. Methods: This retrospective study included hemodynamically stable blunt trauma patients treated from 2021 to 2022 in our hospital. Patients were grouped by CAT+ or CAT- status. Propensity score matching (PSM) was used to balance baseline characteristics. Logistic regression analyses evaluated the predictive value of PP, while receiver operating characteristic curve (ROC) analysis was performed to determine optimal thresholds in elderly patients (age >60 years). Results: Of 456 patients, 65 (14.3%) were classified as CAT+. PP ≤40 mmHg was an independent predictor of CAT+ before PSM (OR = 5.931; 95% CI, 2.648-13.284; P < 0.001) and after PSM (adjusted OR = 4.579; 95% CI, 1.193-10.958; P = 0.016). In elderly patients, the optimal PP threshold for CAT+ was ≤41.5 mmHg, with an area under the curve (AUC) of 0.822 (95% CI, 0.724-0.921). Conclusion: PP is a reliable predictor of critical hemorrhage in hemodynamically stable blunt trauma patients and elderly subgroups, supporting its use in trauma care.

Source: Pakistan Journal of Medical Sciences

DOI: 10.12669/pjms.41.12.11505

Authors: Juan Peng, Dandan Jiang, Shan Liu, Chanjuan Yang

Institution: University of South China

Language: English

Topic: Trauma, Hemostasis, Coagulopathy, Resuscitation

Subfield: Critical Care and Intensive Care Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $400