Breaking the Pattern: Unmasking a Rare Form of Cushing Disease
Year: 2025
Type: article
Study design: Case Report
Abstract: A bstract Cushing’s disease is a rare cause of Cushing syndrome resulting from an ACTH-secreting pituitary adenoma. It may present with overlapping clinical features and conflicting diagnostic tests. It is most often characterized by partial suppression of cortisol with high-dose dexamethasone. However, in rare cases, cortisol levels remain non-suppressible even with supraphysiological doses. We present a case of pituitary-dependent hypercortisolism with absent suppression on high-dose dexamethasone, highlighting the diagnostic challenges and implications for management.
Authors: Md. Rakibur Rahman, Tanjina Zannat, Md. Mohiuddin Sarker, Soma Sarker, Syeda Atika Sultana, Md. Humayun Kabir, Md. Mahmud Hasan, Sutopa Saha Podder, Rabia Zaman
Institution: Dhaka Medical College and Hospital
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4417243377