Work

Multiorgan impact of neonatal encephalopathy: higher burden in preterm infants

Year: 2025

Type: article

Abstract: Neonatal hypoxic-ischemic encephalopathy (HIE) is the leading cause of neonatal encephalopathy (NE) and is associated with multi-organ dysfunction (MOD) and long-term complications. 1 The impact of oxygen deprivation and redistribution of cardiac output to vital organs is likely higher in preterm neonates (born before 35 weeks of gestation) with the added burden of hypoxia and immaturity. 2 Studies typically focus on term infants, due to limitation of the neurological assessment in preterm examination and lack of therapeutic options in vulnerable preterm group. 3

Source: Pediatric Research

DOI: 10.1038/s41390-025-04617-6

Authors: Lina F. Chalak, Lynn Bitar, Paywand Baghal, Khawar Nawaz, Srinivas Kota

Institution: The University of Texas Southwestern Medical Center

Language: English

Topic: Neonatal and fetal brain pathology

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,390