Work

Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens

Year: 2025

Type: article

Abstract: DNA Origami Nanostructures In their Research Article (10.1002/sstr.202500246), Yixin Zhang, Adrian Keller, and co-workers use click chemistry to decorate DNA origami nanostructures with the small molecule antibiotic vancomycin. The vancomycin-modified DNA origami nanostructures show efficient and robust binding to the surfaces of various Gram-positive and Gram-negative bacteria without affecting bacterial growth.

Source: Small Structures

DOI: 10.1002/sstr.70201

Authors: Özge Coşkuner Leineweber, Bhanu K. Pothineni, Nils Schumann, Ulrike Hofmann, Christin Möser, David M. Smith, Guido Grundmeier, Yixin Zhang, Adrian Keller

Institutions: Paderborn University, Center for Molecular Bioengineering, Technische Universität Dresden, Fraunhofer Institute for Cell Therapy and Immunology

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $4,110

OpenAlex ID: W4417246935

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