Work

Optogenetic Rescue Reveals Spatiotemporal Rules of Germ-Layer Patterning

Year: 2025

Type: preprint

Source: SSRN Electronic Journal

DOI: 10.2139/ssrn.5894663

Authors: Naomi Baxter, Robert Piscopio, Joseph Rufo, Dasol Han, Isobel Whitehead, Jasmine Dhillon, Siddharth S. Dey, Maxwell Z. Wilson

Institutions: University of California, Santa Barbara, Altos Labs

Language: English

Topic: Developmental Biology and Gene Regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institutes of Health

Awards: A marker-free technology for mapping the epigenome of cell types in mammalian tissues, Shining light on the mechanisms of primate gastrulation: development of high-throughput, optogenetic tools for understanding embryonic development, Dissecting the role of Erk signaling dynamics in positioning and coordinating germ layer fates, Optical dissection of human embryonic germ layer patterning mechanisms using microengineered stem cell models, Understanding DNA methylation reprogramming dynamics during preimplantation development using single-cell sequencing

OpenAlex ID: W4417253970

Cites: 72

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