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Old Bug, New Challenge: Invasive Group A Streptococcus and a Rare Pediatric Holospinal Epidural Abscess

Year: 2025

Type: article

Abstract: Invasive group A Streptococcus (iGAS) infections have risen in the post-COVID-19 era, with significant morbidity and mortality in children. Spinal epidural abscess (SEA) is a rare, life-threatening condition, and pediatric cases are scarcely reported. SEA caused by iGAS is even more unusual, with only sporadic case reports in the literature. Herein, a challenging case of pediatric SEA due to iGAS is described, raising awareness of this clinical entity. An otherwise healthy 18-month-old girl presented with a three-day history of gait disturbance, high temperature, and seizures. Lumbar puncture revealed pus, and cultures grew group A Streptococcus. Magnetic resonance imaging demonstrated a holospinal epidural abscess. The patient was managed conservatively with serial epidural needle drainage and prolonged intravenous antibiotics. She achieved complete clinical and radiological recovery without neurological sequelae. Pediatric SEA is rare, but early recognition and appropriate management are essential to prevent irreversible complications. Clinicians should remain vigilant for spinal complications of iGAS infections to optimize outcomes.

Source: Cureus

DOI: 10.7759/cureus.98990

Authors: Natalia Syrimi, Despoina Maritsi, Alma Sulaj, Maria Tsolia, Angeliki Syngelou

Institutions: National and Kapodistrian University of Athens, Panagiotis & Aglaia Kyriakou Children's Hospital

Language: English

Topic: Infectious Diseases and Tuberculosis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4417256947