Postoperative meningitis due to carbapenemase-producing Klebsiella pneumoniae : A case report and literature review
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Postoperative meningitis is a serious complication in neurosurgery. Early diagnosis and appropriate management are essential to reduce its significant morbidity and mortality. Case Description: We report the case of a 76-year-old patient who underwent evacuation of a posterior fossa hematoma. On postoperative day 19, he presented with fever and surgical wound necrosis. Surgical revision revealed a collection fistulized to the skin. Cerebrospinal fluid analysis and intraoperative samples confirmed postoperative meningitis caused by multidrug-resistant Klebsiella pneumoniae , susceptible only to colistin and fosfomycin. Despite treatment adjustment, the patient’s condition worsened, and he died 12 days after surgical revision due to massive pulmonary embolism. Conclusion: This case highlights the severity of postoperative meningitis due to extensively drug-resistant K. pneumoniae and underlines the importance of early diagnosis, bacteriological analysis of surgical samples, and rapid adaptation of antibiotic therapy in specialized settings.
Source: Surgical Neurology International
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4417265173