Temporal epilepsy associated with hippocampal focal cortical dysplasia
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Focal cortical dysplasia (FCD) is a congenital abnormality of the cerebral cortex and a common cause of epilepsy. However, FCD in the hippocampus is rare. Case Description: A 30-year-old woman was admitted to the hospital because of seizures. Brain magnetic resonance imaging showed focal cortical thickening of the right medial temporal lobe cortex. The patient underwent a right-sided anteromedial temporal lobectomy. Pathologic examination showed disorganized cortical gray matter tissue with large dysmorphic cortical neurons, supporting a FCD diagnosis. The histological findings of hippocampal sclerosis were not found. Conclusion: The present case is a rare case of dysmorphic neurons without histological findings of sclerosis in the hippocampus reported. Recognizing more hippocampal FCD-related epilepsy cases is essential to better understanding the condition.
Source: Surgical Neurology International
Authors: Thi Phuoc Yen Tran, The Khanh Dang, Nu Tra My Ton, Thi Hong Khang Bui, Minh Chau Tran, Nhu Phuc Tran, Van Tri Truong
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4417265178