The use of antibiotic impregnated fenestrated screws in instrumentation for osteomyelitis: A case report
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Cervical osteomyelitis presents significant treatment challenges due to its potential for recurrence. Standard approaches, including intravenous antibiotics and surgical debridement, are essential but may fall short in managing complex infections. In this case report, we aim to document our experience with the use of antibiotic-packed screws to treat recurrent cervical spine osteomyelitis. Case Description: (MSSA) C1-C2 osteomyelitis presented with acute neck pain and was found to have atlanto-axial instability and an epidural abscess. He was treated with washout and posterior fusion and instrumentation, during which screws were packed with vancomycin powder before placement to achieve localized antibiotic release. Postoperatively, the patient experienced marked improvement in pain and mobility. Follow-up imaging showed stable instrumentation and alignment. At 6 months postoperatively, the patient was pain-free and remained off antibiotics without evidence of recurrence. Conclusion: This case highlights antibiotic-packed screws as a potential adjunctive approach for managing refractory cervical spine osteomyelitis, combining targeted infection control with immediate mechanical support.
Source: Surgical Neurology International
Institution: University of Cincinnati
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4417265182