Work

First identification of a multidrug-resistant Pseudomonas kurunegalensis clinical isolate co-carrying blaAFM-1 and blaIMP-1 in China

Year: 2025

Type: article

Abstract: OBJECTIVES: in a multidrug-resistant Pseudomonas kurunegalensis (P. kurunegalensis) isolate obtained from human urine using whole-genome sequencing. METHODS: underwent a comprehensive investigation that included antimicrobial susceptibility testing, conjugation assays, whole-genome sequencing and bioinformatic analyses. To depict the evolutionary dynamics of P. kurunegalensis strains on a global scale, a phylogenetic tree was generated based on single nucleotide polymorphisms of core genomes. RESULTS: dissemination. CONCLUSIONS: and tmexC3D2-toprJ1 were harboured by P. kurunegalensis. We suggested that ST114 P. kurunegalensis may serve as a reservoir for resistance genes.

Source: Journal of Global Antimicrobial Resistance

DOI: 10.1016/j.jgar.2025.12.007

Authors: Shuwei Fan, Yuzhuo Gong, Chunxiao Chen, Jingchao Shi, Cong Wu

Institutions: Zhejiang University, Huazhong University of Science and Technology, Jinhua Central Hospital

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,890