Work

Fractal Dimension of High-Risk Neuroblastoma Vascularity in MRI Is Associated with Chemotherapy Response and Event-Free Survival

Year: 2025

Type: article

Abstract: Fractal analysis of vascularity using routine MRI in primary high-risk neuroblastomas predicted local tumor tissue response to chemotherapy at diagnosis and stratified prognosis of patient subgroups after chemotherapy.

Source: Radiology Imaging Cancer

DOI: 10.1148/rycan.250070

Authors: Florian Michallek, Marc Dewey, Barbara Hero, Kathrin Hauptmann, Simon Veldhoen, Verena Paulsen, Kathy Astrahantseff, Hedwig E. Deubzer, Thorsten Simon, Angelika Eggert, Theresa M. Thole-Kliesch

Institutions: Mie University, Charité - Universitätsmedizin Berlin, University of Cambridge, Royal Papworth Hospital, British Heart Foundation, Papworth Hospital NHS Foundation Trust, University of Cologne, Max Delbrück Center, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Deutsches Konsortium für Translationale Krebsforschung

Language: English

Topic: Neuroblastoma Research and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Deutsche Forschungsgemeinschaft, Deutsche Krebshilfe

Awards: Untersuchung der Fraktalanalyse zur Charakterisierung und Quantifizierung der myokardialen Ischämie bei der Perfusionsbildgebung, G4470063534, G7588888808, G7953833968

OpenAlex ID: W4417277569

FWCI: 1.123

Cites: 35

Cited by: 2

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